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Updated: Feb 15, 2026

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一个统一的框架,结合线性和3D分子特征,用于强大的药物蛋白相互作用预测

Chang Sun1, Zichen Qin2, Minglei Li1

  • 1Centre for Bioinformatics and Intelligent Medicine, College of Computer Science, Nankai University, Tianjin 300071, China.

Cell reports methods
|February 13, 2026
PubMed
概括

PointDPI使用线性和3D特征预测药物蛋白相互作用 (DPI),提高未见分子的准确性. 四个预测的DPI经过实验验证,显示了对各种疾病的治疗潜力.

关键词:
3D分子结构 3D分子结构CP:计算生物学 计算机生物学这就是PDE4B.多模式结构对齐调整拓关系的保存 拓关系的保存在湿实验室实验中进行实验.

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