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酸奶和麦消费对肠道微生物群的影响:一项随机交叉研究,显示个体反应和一般性
Kerstin Thriene1, Virginie Stanislas2, Kun D Huang3
1Institute for Prevention and Cancer Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, 79110 Freiburg, Germany; Institute of Microbiology, Friedrich Schiller University, Jena, Germany.
The Journal of nutrition
|February 13, 2026
概括
每天摄入酸奶和麦片对健康个体的肠道微生物群的影响很小. 虽然酸奶暂时增加了特定的细菌,但整体肠道健康标志物保持不变,强调了微生物群的弹性.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 由于潜在的益生菌和益生菌效应,酸奶和卷经常与肠道健康益处有关.
- 这些影响还没有得到充分的研究,特别是在正常饮食的健康人群中.
研究的目的:
- 调查每天消费酸奶和麦对肠道微生物组成的影响.
- 评估二次结果,包括便代谢物和基于血液的健康标志物.
主要方法:
- 一个随机的,开放的,两期的交叉试验,涉及110名健康参与者.
- 参与者每天要么单独食用酸奶,要么每天与麦卷一起食用酸奶,并有洗期.
- 分析了便和血液样本,使用元基因组测序,代谢学和各种健康标志物评估.
主要成果:
- 酸奶的消费导致了酸奶相关细菌的暂时增加,特别是Streptococcus thermophilus.
- 在Prevotella占主导地位的小组中,麦增加了微生物均性,减少了个体间的分歧.
- 在便短链脂肪酸 (SCFA) 或一般人类健康标志物中没有发现显著变化.
结论:
- 健康个体的肠道微生物群通常是稳定的,并且能够抵御短期的饮食变化.
- 个体反应的变化表明可能需要个性化的饮食建议.
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