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药物负载对含有表面活性剂的无形固体分散物的溶解行为和稳定性的影响

Dijia Liu1, Shu Li1, David S Jones1

  • 1Pharmaceutical Engineering Group, School of Pharmacy, Queen's University of Belfast, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland, United Kingdom.

International journal of pharmaceutics
|February 13, 2026
PubMed
概括

药物负载影响无形固体的分散稳定性和溶解. 三级系统的稳定性较差,溶解下降速度比二级系统更快,药物负载较高.

关键词:
无形固体分散的分散.毒品装载 毒品装载热挤出是一种热的方法.在Kolliphor® RH40 RH40中使用.这种药物是Lumefantrine.化成的过程在Soluplus®中使用Soluplus®.

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