声带功能障碍/诱导性喉阻塞 (VCD/ILO) 作为对过敏反应的模仿:一个回顾性队列研究
Paul Satouris1, Georgina Hallam2, Ke Li Chow3
1Clinical Immunology and Allergy, John Hunter Hospital, Newcastle, Australia; NSW Health Pathology, Immunology, Newcastle, Australia.
The journal of allergy and clinical immunology. In practice
|February 13, 2026
概括
声带功能障碍 (VCD) 或诱导性喉阻塞 (ILO) 是一种常见的疾病,在成年人中模仿过敏反应. 承认VCD/国际劳工组织
科学领域:
- 过敏和免疫学 过敏和免疫学
- 肺部病理学 肺部病理学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 声带功能障碍 (VCD),也称为诱导性喉阻塞 (ILO),呈现为偶发性上呼吸道阻塞.
- VCD / ILO 症状可能与过敏反应的症状非常相似,导致诊断挑战.
- 准确的区分对于适当的患者管理和避免不必要的治疗至关重要.
研究的目的:
- 为了确定VCD/ILO在成年人中的患病率,因疑似过敏症而转诊到过敏诊所.
- 识别不同的临床标志物,使VCD/ILO与实际过敏症区分开来.
主要方法:
- 对于疑似过敏反应的成年患者的回顾性分析,他们被转诊到三级过敏诊所.
- 将患者分为确认的VCD/ILO,疑似的VCD/ILO,过敏反应或其他类别.
- 在VCD/ILO和过敏反应组之间比较人口统计,触发因素,并发症,临床特征,调查和医疗保健利用情况.
主要成果:
- 在8.3%的患者 (确诊) 和24.1% (包括疑似病例) 中发现了VCD/ILO.
- VCD/ILO病例主要表现为上呼吸道症状,如喉紧张,,听力障碍和咳,与过敏反应不同.
- 系统性症状 (疹,胃肠道,心血管) 在VCD/ILO中明显不太常见,VCD/ILO也有更多不同的触发因素,特别是气溶化学物质,具有罕见的IgE敏感性.
结论:
- 在怀疑过敏反应的成年人中,VCD/ILO是常见的差异诊断.
- 典型的临床特征和特定的触发特征有助于区分VCD/ILO和过敏反应.
- 更好地识别VCD/ILO可以防止误诊,降低医疗保健成本,并改善患者的治疗结果.
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