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Updated: Feb 15, 2026

Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
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将SARS-CoV-2主蛋白酶捕获到短暂的人工生菌因子中,以实现高产量的表达和简化净化

Pavel Novotný1, Adéla Moravcová2, Veronika Nováková3

  • 1Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Prague, Czech Republic.

International journal of biological macromolecules
|February 13, 2026
PubMed
概括

三种表达策略产生高质量的SARS-CoV-2主要蛋白酶 (Mpro) 用于研究. 所有方法都产生具有真实N-终端的活性Mpro,适合生物化学和结构研究.

关键词:
蛋白质净化 蛋白质的净化在SARS-CoV-2中,主要的蛋白酶是SARS-CoV-2.这就是Zymogen.

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