相关实验视频
Updated: Feb 15, 2026

09:55
In vitro Cell Migration and Invasion Assays
Published on: June 1, 2014
141.5K
检测检查淋巴细胞入侵的测试
Alexander A Lekan1, Rachael E Maynard1, Louis M Weiner1
1Department of Oncology, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, United States.
Methods in cell biology
|February 13, 2026
概括
研究免疫细胞迁移对于癌症免疫疗法至关重要. 新的二维和三维方法有助于研究人员评估免疫细胞入侵瘤微环境 (TME),以改善癌症治疗策略.
科学领域:
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
- 细胞生物学 细胞生物学
背景情况:
- 免疫细胞迁移对于对抗感染,自身免疫和癌症至关重要.
- 有效的癌症免疫疗法,特别是固体瘤,依赖于免疫细胞透到瘤微环境 (TME).
- 了解免疫细胞入侵的现有局限性阻碍了癌症治疗的有效性.
研究的目的:
- 提出新的2D和3D体外方法来研究免疫细胞迁移和入侵.
- 为人类免疫细胞入侵研究提供更好地回顾瘤微环境 (TME) 的工具.
- 推进癌症免疫疗法中免疫细胞透屏障的研究.
主要方法:
- 开发和调整2D和3D体外模型.
- 设计用于评估免疫细胞的迁移和入侵能力的技术.
- 专注于与癌症免疫治疗相关的T细胞和自然杀手 (NK) 细胞.
主要成果:
- 建立了可适应的2D和3D方法来评估免疫细胞入侵.
- 提供了一个研究免疫细胞在模拟TME中的行为框架.
- 适用于理解免疫疗法挑战的证明技术.
结论:
- 描述的二维和三维方法对于调查免疫细胞入侵有价值.
- 这些技术可以帮助开发更有效的癌症免疫疗法.
- 对免疫细胞迁移的进一步研究对于推进癌症治疗至关重要.
相关概念视频
Urologic Endoscopic Procedure: Cystoscopic Examination
3.5K
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
3.5K
Mechanical Ventilation II: Invasive Ventilation
794
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
794
Enzyme-Linked Immunosorbent Assay
17.8K
In 1971, Peter Perlman and Eva Engvall developed an Enzyme-linked immunosorbent assay (ELISA or EIA). ELISA differs from western blot in that the assays are conducted in microtiter plates or in vivo rather than on an absorbent membrane.
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen. Enzyme-substrate reaction allows the antigen to be visualized or...
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen. Enzyme-substrate reaction allows the antigen to be visualized or...
17.8K
What is the Immune System?
133.1K
Overview
133.1K
Vaccinations
51.9K
Overview
51.9K
Inflammation
62.5K
Overview
62.5K

