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糖尿病心肌病在低收入和中等收入国家中的患病率:系统审查协议
A Arowolo1, L D M Bennie2, W Mahmoud3
1Biomedical Research and Innovation Platform, South African Medical Research Council, Cape Town, 7500, South Africa. afolake.arowolo@mrc.ac.za.
Systematic reviews
|February 14, 2026
概括
糖尿病心肌病 (DbCM) 在低收入和中等收入国家 (LMICs) 的患病率正在上升. 这一系统性审查将估计LMIC中2型糖尿病 (T2DM) 的成年人中DbCM患病率,以告知预防工作.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病 (T2DM) 在低收入和中等收入国家 (LMICs) 造成越来越大的健康负担.
- 糖尿病心肌病 (DbCM),心肌功能障碍独立于其他原因,是一个重要的T2DM并发症,可能导致心力衰竭.
- 与高收入环境相比,LMIC中DbCM的患病率和分布并不清楚.
研究的目的:
- 系统地审查和估计LMIC中T2DM成年人中DbCM的综合流行率.
- 描述DbCM流行率的区域差异.
- 确定导致DbCM流行异质性的因素,如诊断方法,血糖控制和人口统计.
主要方法:
- 遵守PRISMA-P和JBI系统审查指南.
- 在多个数据库 (PubMed,Scopus,Web of Science,Embase,AJOL,EBSCOhost) 和灰色文献中进行全面的文献搜索.
- 包括来自LMIC的观察性研究,通过客观心脏成像诊断DbCM,进行独立查,提取数据,并由两名审查员评估偏差风险.
主要成果:
- 在数据可比的情况下,将使用随机效应元分析计算DbCM的聚合流行率估计.
- 将使用通用线性混合模型来解释研究变异性.
- 将使用I2统计来评估异质性,并通过子组分析来探索;如果元分析是不可行的,将使用叙事综合.
结论:
- 这一审查将为LMICs的DbCM负担提供关键估计.
- 调查结果将为卫生系统的规划和为糖尿病护理的资源分配提供信息.
- 生成的证据将指导未来的研究和预防策略,以减轻与糖尿病有关的心力衰竭.
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