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Updated: Feb 15, 2026

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通过优先考虑来自人类遗传关联研究的发现,推动治疗系统性硬化症的药物开发

Michael Hughes1,2,3, Zsuzsanna H McMahan4, Shervin Assassai4

  • 1Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Science, School of Biological Sciences, Faculty of Biological Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

Rheumatology (Oxford, England)
|February 14, 2026
PubMed
概括

这项研究通过整合人类遗传学和生物信息学,确定了89种针对系统性硬化症 (SSc) 的潜在药物. 新发现包括神经递质向疗法,为SSc治疗提供廉价的重新定位机会.

关键词:
临床试验是指临床试验中的临床试验.药物重用是为了改变药物的用途.硬化皮质硬化皮质 (scleroderma) 是一种疾病.系统性硬化症 系统性硬化症

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