基于多式医疗数据和心血管热传递模型的个性化血液动力学分析
Yongtao Liu1, Huimin Chen1, Xiaoling Ding1
1Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education, School of Energy and Power Engineering, Dalian University of Technology, Dalian, China.
International journal for numerical methods in biomedical engineering
|February 14, 2026
概括
这项研究整合了心血管和传热模型,用于非侵入性生理监测. 结合的模型准确地预测血流和皮肤温度,有助于心血管疾病查.
科学领域:
- 生理学建模 生理学建模
- 心血管动力学的动态
- 热生理学 热生理学
背景情况:
- 血液流量和温度的非侵入性测量对于医疗保健和心血管疾病查至关重要.
- 现有的模型往往缺乏心血管血液动力学和热调节之间的整合.
研究的目的:
- 开发和验证一个集成的单维 (1D) 心血管模型,并配合一块式参数传热模型.
- 评估个性化的心血管血动力学和皮肤温度调节.
- 在不同的生理条件下探索血液流动的变化.
主要方法:
- 整合多式人体数据与1D动脉树和一次性参数传热模型.
- 使用辐射压力和流速波形来个性化外围阻抗和脉冲波速率.
- 结合心血管和传热模型,用于热血流分析.
- 预测皮肤血液 perfusion 和组织层厚度.
主要成果:
- 预测和验证了个性化的中央大动脉压力.
- 结合模型有效地模拟了受试者的血流波形和皮肤温度.
- 非侵入性脉冲波设备可以预测和校准中央大动脉压力.
- 皮肤温度的变化与周围血液流动的动态相关.
结论:
- 综合热血流模型为非侵入性心血管评估提供了一个强大的平台.
- 这种方法增强了对皮肤温度和血液流动之间的关系的理解.
- 该模型支持心血管疾病的早期查和个性化的生理监测.
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