修改的脆弱指数-5作为急性囊切除术后术后并发症的预测指标
Erdinc Dincer1, Orkunt Ozkaptan1, Cengiz Canakci1
1Department of Urology, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkiye.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|February 14, 2026
概括
更高的修改脆弱指数-5 (mFI-5) 评分预测了膀癌激进囊切除术后更多的重大并发症. 该指数可以帮助指导肌肉侵入性膀癌 (MIBC) 患者的治疗决策.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
背景情况:
- 膀癌是一个重大的健康问题.
- 激进囊切除术 (RC) 是肌肉侵入性膀癌 (MIBC) 的首要治疗方法.
- 评估术前风险因素对于优化患者的治疗结果至关重要.
研究的目的:
- 评估修改脆弱指数-5 (mFI-5) 对肌肉侵入性膀癌 (MIBC) 患者激进囊切除术 (RC) 后术后并发症的预测能力.
主要方法:
- 对184名接受MIBCRC的患者进行了回顾性分析.
- 患者被分为高 (mFI-5 ≥2) 和低 (mFI-5 <2) 风险组.
- 在使用奇平方测试的组之间比较了并发症率.
主要成果:
- 高风险组 (mFI-5 ≥2) 的重大并发症发生率明显高 (Clavien-Dindo ≥3) (30.86%对比17.47%,p=0.033).
- 胃肠道并发症在高风险组中更频繁 (p=0.005).
- 高风险组经历了更长的住院时间.
结论:
- 升高的mFI-5得分与RC后严重并发症的发病率增加有关.
- 在MIBC患者中,mFI-5是风险分层和治疗规划的宝贵工具.
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