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Xerostomia 在患有或没有同时出现口腔灼热疼痛和/或失听症的患者中
Yoon-Jai Hwang1, Hong-Seop Kho1,2
1Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
Journal of oral rehabilitation
|February 14, 2026
概括
口腔干燥 (xerostomia) 的严重程度与唾液腺功能有关,当它单独发生时. 然而,当口腔干燥伴随着口腔灼热疼痛或失声症时,心理困扰和症状强度成为更重要的因素.
科学领域:
- 口腔医学是指口腔医学.
- 牙科研究 牙科研究
- 症状学研究 症状学研究
背景情况:
- Xerostomia (口腔干燥) 的严重程度往往与客观的唾液流量率缺乏相关性.
- 同时的口腔灼热疼痛或无声症对异口腔的影响仍然不太清楚.
研究的目的:
- 为了研究口腔灼热疼痛和/或听力障碍如何影响xerostomia的感知严重程度.
- 根据症状呈现来区分导致异口症严重程度的因素.
主要方法:
- 对396名口腔干燥患者的回顾性分析.
- 分类为单独的异口症 (146名患者) 与异口症与口腔灼热疼痛/失声症 (250名患者) 相比.
- 通过问卷,唾液流量测试,Candida培养和心理评估收集数据;用于分析的多重线性回归.
主要成果:
- 两组之间在自我报告的异位症严重程度上没有显著差异.
- 对于单独的异口症,严重程度与较低的唾液流量和较高的Candida定居度相关.
- 对于带有疼痛/听觉障碍的异口症,严重程度与味觉障碍,口腔疼痛强度和心理困扰有很强的相关性,与唾液流动的相关性较弱.
结论:
- 在孤立的病例中, Xerostomia 的严重程度主要与唾液腺功能有关.
- 在与口腔燃烧疼痛/无声症并发的异口症病例中,症状严重程度和心理困扰比唾液流量更有影响.
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