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Updated: Feb 15, 2026

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线粒体局部化的FABP4通过维护线粒体恒常性来抑制依赖铁灭的结核菌菌的传播

Tingting Zhao1, Xinyu Hu1, Ju Li1

  • 1State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Basic Medical Sciences, Jilin University, Changchun, China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|February 14, 2026
PubMed
概括

结核菌菌感染抑制了线粒体脂肪酸结合蛋白4 (FABP4),促进了病原体的传播. 恢复FABP4可以抑制铁亡并减少细菌的增殖,为结核病提供新的治疗点.

关键词:
在Fabp4中使用.铁性化 (ferroptosis) 是一种脂质过氧化过氧化线粒体的恒常状态是线粒体的恒常状态结核病是一种肺结核病.

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