使用4D流MRI量化肝动脉血流量:一种体内可行性和可重复性研究
Anne van den Brekel1, Marnix C Maas2, Ilse M Spenkelink2
1Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands. Anne.vandenBrekel@radboudumc.nl.
Magma (New York, N.Y.)
|February 14, 2026
概括
四维 (4D) 流动MRI可以量化肝动脉血流 (HABF),但显示出显著的扫描-重新扫描变化. 获取因素是HABF测量中这种变化的主要来源.
科学领域:
- 医疗成像医学成像
- 心血管磁力共振成像 (MRI) 的方法
- 肝病学 肝病学是一种肝病学.
背景情况:
- 量化肝动脉血流 (HABF) 对于诊断和管理肝脏疾病至关重要.
- 四维 (4D) 流动MRI为非侵入性HABF评估提供了潜力.
- 了解HABF的4D流MRI的可行性和可重复性是必不可少的.
研究的目的:
- 评估4D流MRI的可行性和可重复性,以量化HABF.
- 为了确定HABF的4D流MRI测量可变性的来源.
- 将4D流动MRI测量与传统的2D技术进行比较.
主要方法:
- 一项前性研究,涉及23名健康志愿者和12名肝病患者.
- 使用3T,2D和4D流动MRI序列进行的采集.
- 分析包括可行性,扫描-重新扫描可重复性 (CVwithin),以及使用Bland-Altman的2D流程的协议.
主要成果:
- 4D流MRI显示,CHA可视化的可行性率为83%.
- 个体内变化系数 (CVwithin) 在12-30%之间.
- 与2D流量相比,4D流量MRI显示了显著的差异,高估了面积,低估了速度/流量.
结论:
- 在健康和患病的肝脏中,4D流动MRI是可行的HABF量化.
- 存在大量的扫描-重新扫描变化,主要是由与收购相关的因素驱动的.
- 虽然可行,但需要进行技术改进,以减少临床应用的变化.
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