相关实验视频

Updated: Feb 16, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

传统的吞疗法加上神经肌肉电刺激在多发性硬化症的有效性:一个随机对照试验

Maria Grazia Grasso¹, Giampaolo Brichetto², Marco Rovaris³

¹Santa Lucia Foundation IRCCS, Via Ardeatina, 306 Rome, Italy.

Multiple sclerosis and related disorders

|February 14, 2026

概括

神经肌肉电刺激 (NMES) 与吞疗法相结合,是一种安全有效的治疗方法,用于治疗患有多发性硬化症 (pwMS) 的人的吞困难,特别是那些严重残疾的人.

科学领域:

神经学神经学
康复医学康复医学康复医学
吞障碍吞障碍吞障碍

背景情况:

缺食症是患有多发性硬化症 (pwMS) 的人常见和严重的问题.
目前的补偿策略对于pwMS的吞障碍并不能完全恢复吞功能.
神经肌肉电刺激 (NMES) 显示出缺食症的潜力,但在pwMS中缺乏强有力的证据.

研究的目的:

评估NMES与标准吞疗法相结合的可行性和有效性,用于pwMS的吞障碍.
为了比较NMES加治疗与假刺激加治疗.

主要方法:

这是一项双盲,随机,安慰剂对照试验,涉及101名失性 pwMS.
参与者接受了NMES加上常规的吞练习 (TST-NMES) 或假刺激加上相同的治疗 (TST-S).
使用ASHA评分测量结果,疾病严重程度通过EDSS进行评估.

主要成果:

两组患者的消化障碍随着时间的推移而有所改善.
在TST-NMES组中,严重残疾患者 (EDSS ≥7) 显示出显著更大的ASHA评分改善.
基线ASHA分数预测了结果,而EDSS只影响了对照组. 没有报告任何不良影响.

结论:

与标准吞疗法相结合的NMES是一种可行且有效的干预措施,用于pwMS的吞障碍.
这些好处在残疾较严重的人群中尤为明显.
需要进一步的大规模随机试验来证实这些发现.

关键词:

消化不良症是什么消化不良症多发性硬化症是多发性硬化症.神经肌肉电刺激 (NMES) 是一种神经肌肉电刺激.随机对照试验是随机对照试验.吞疗法是一种吞治疗.

更多相关视频

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

相关概念视频

Upper GI Series: Barium Swallow

Upper GI Series: Barium Swallow

The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...

Self-Efficacy

Self-Efficacy

Self-efficacy is the belief in one's capacity to organize and execute actions necessary to manage prospective situations. This belief significantly influences how individuals approach goals, tasks, and challenges across different domains of life.Psychological and Educational ImpactsIndividuals with strong self-efficacy are more resilient in the face of difficulties. They are more likely to adopt effective problem-solving strategies, persist through obstacles, and regulate emotions such as...

Trial and Error and Algorithm

Trial and Error and Algorithm

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...

Clinical Trials: Overview

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...

Clinical Trials

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...

Random Error

Random Error

Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...