荷莫平素通过调节YES相关蛋白1调节高葡萄糖诱导的血管内皮屏障功能障碍,从而缓解高葡萄糖诱导的血管内皮屏障功能障碍

Xulu Li1, Jingwen Wang1, Lei Wang1

  • 1School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Longmian Avenue, Nanjing 211198, China.

概括

同类植物素 (HPG) 通过调节YAP1/SIRT1/HMGB1通路来保护血管内皮壁 (VE) 免受高葡萄糖损伤. 这种天然化合物在治疗糖尿病大血管并发症方面表现有前途.

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