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通过虚拟查,合成,体外试验和分子动力学模拟来发现新型ULK1抑制剂

Yifan Yang1, Huijie Han1, Jingjing Li1

  • 1College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, PR China.

Bioorganic chemistry
|February 14, 2026
PubMed
概括

研究人员使用计算和实验方法发现了用于癌症治疗的新型ULK1抑制剂. 有希望的候选人D1-D3显示强大的纳米分子活性,为新的抗癌药物开发提供了基础.

关键词:
在体外测定试验.分子动力学模拟模型有机合成 有机合成ULK1 抑制剂的使用.虚拟选是一个虚拟的选.

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