在化疗期间探索食道癌患者症状网络的动态:一个交叉滞后的面板网络分析
Changqing Sun1, Dequan Sun1, Hui Yang2
1School of Nursing and Health, Zhengzhou University, Zhengzhou, Henan, China.
概括
在接受化疗的食道癌患者中,疼痛和吞困难是关键的早期症状. 后来,疲劳和恶心变得更有影响力,指导特定阶段的症状管理策略.
科学领域:
- 在瘤学瘤学.
- 心理测量 心理测量 心理测量
- 网络分析 网络分析
背景情况:
- 接受化疗的食道癌症患者经历复杂的症状集群.
- 了解时间症状动态对于有效的支持性护理至关重要.
研究的目的:
- 在化疗期间检查食道癌症患者的纵向症状网络.
- 为了确定特定阶段的影响性症状和时间关联.
主要方法:
- 在中国河南,对339名参与者进行了长度研究.
- 使用了医疗保健. 安德森的症状库存胃肠癌模块 (MDASI-GI).
- 应用交叉滞后面板网络分析来评估症状动态.
主要成果:
- 在治疗早期 (T1→T2),疼痛和吞困难是最有影响力的.
- 最强早期关联:从疼痛到呼吸短促 (β=0.282).
- 在治疗后期 (T2→T3),疲劳和恶心变得最有影响力,疲劳到呼吸短促是最强的关联 (β=0.454).
结论:
- 在食道癌化疗期间,症状的影响力会动态转移.
- 确定了关键症状 (疼痛,吞困难,疲劳,恶心) 和它们的时间联系.
- 研究结果支持基于阶段的,基于网络的症状管理方法.
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