慢性四肢威胁性缺血的疼痛管理:一个多中心的横截面研究
Henry Davies1, Ahmed Boalot2, Toby Mountain2
1University of Leeds, UK.
Annals of vascular surgery
|February 14, 2026
概括
慢性四肢威胁性缺血症 (CLTI) 患者的疼痛管理不足,大多数患者经历严重的疼痛影响日常生活. 目前的世卫组织止痛指南可能对血管疼痛无效,需要进一步研究以找到更好的策略.
科学领域:
- 血管外科 血管外科
- 疼痛管理 疼痛管理
- 患者的治疗结果.
背景情况:
- 慢性四肢威胁性缺血症 (CLTI) 呈现出持续的缺血性休息疼痛.
- 目前的疼痛管理策略,比如世卫组织的止痛药梯,对于血管疼痛可能是不理想的.
- 对于CLTI患者来说,有效的疼痛缓解仍然是一个重大的临床挑战.
研究的目的:
- 评估住院的CLTI患者疼痛管理的有效性.
- 评估疼痛严重程度及其对日常功能的影响,使用简要疼痛清单 (BPI) 评分.
- 为了确定目前对CLTI的止痛疗法的不足.
主要方法:
- 一项涉及104名患有CLTI的住院血管患者的横截面研究.
- 数据收集包括简要疼痛清单 (BPI),以测量疼痛严重程度和功能影响.
- 分析止痛疗法,重血管化状态和截肢病史.
主要成果:
- 80.7%的患者报告中度至重度疼痛 (≥5/10).
- 尽管使用过多的类药物和强烈的阿片类药物,但39.6%的患者经历了不足的疼痛缓解.
- 在大多数患者中,疼痛显著干扰了一般活动,情绪,运动和睡眠.
结论:
- 目前,CLTI住院患者的疼痛管理不足.
- 缺血性疼痛机制需要进一步的研究,以开发有效的,基于证据的止痛策略.
- 改善疼痛管理对于提高CLTI患者的生活质量至关重要.
关键词:
乙氨基是一种止痛药是一种止痛药.跨部门研究 跨部门研究住院患者 住院患者缺血 缺血是因为缺血.多中心研究多中心研究片类止痛药 止痛药是一种阿片类止痛药.疼痛管理 疼痛管理疼痛测量方法 疼痛测量方法周围动脉疾病 周围动脉疾病生活质量生活的质量.更多相关视频
06:13Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
Published on: March 1, 2024
1.9K
05:38Author Spotlight: Utilizing Infraorbital Nerve Ligation in Mice for Investigating Trigeminal Neuropathic Pain and Treatment Strategies
Published on: March 8, 2024
2.9K
相关概念视频
Cross-Sectional Research
12.7K
In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
12.7K
Analgesia and Pain Management
2.0K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
2.0K
Finding Volume Using Cross-Sectional Area
102
For solids whose cross-sectional areas vary in a predictable way, volume can be determined by integrating these areas along an axis perpendicular to the slices. This approach is particularly useful for polyhedral solids, where classical geometric formulas may not be immediately applicable. A tetrahedron provides a clear example of how cross-sectional integration can be applied to a three-dimensional object with continuously changing geometry.Consider a tetrahedron with height h and a base that...
102
Profile Leveling and Cross Sections
1.7K
Profile leveling and cross-sections are surveying methods used to determine and document terrain elevations for infrastructure projects such as highways, railroads, canals, and pipelines. These methods provide data for earthwork planning and alignment of proposed routes. Profile leveling involves measuring elevations along a fixed line to create a vertical terrain profile. A surveyor sets up a leveling instrument at the benchmark (BM) and records a backsight (BS) to determine the...
1.7K
Spinal Cord: Cross-sectional Anatomy
5.0K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Gray Matter and its Components
Central to the gray matter is...
5.0K
Chronic Obstructive Pulmonary Disease-V: Management
3.3K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
3.3K
