单细胞转录组分析HSV-1从潜伏感染的树和小鼠三胞胎瘤中重新激活,揭示了不同的分子和细胞过程

Yunshuang Ye1, Erlin Wang1, Mengqiu Yin2

  • 1State Key Laboratory of Genetic Evolution & Animal Models, Yunnan International Joint Laboratory of Zoonotic Viruses, Yunnan Key Laboratory of Biodiversity Information, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China; Department of Neurosurgery, Songjiang Research Institute, Songjiang District Central Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201615, China.

Virologica Sinica
|February 14, 2026
PubMed
概括

人们对简单疹病毒1型 (HSV-1) 再激活的理解不充分. 这项研究揭示了受感染细胞蛋白0 (ICP0) 可能是通过抑制体内自细胞的方法对HSV-1的重新激活至关重要.

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