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Updated: Feb 16, 2026

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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结合来自不同种群的xQTL和全基因组关联研究,改善了可用药物的基因发现

Noah Lorincz-Comi1,2, Wenqiang Song1,2, Xin Chen1,2

  • 1Cleveland Clinic Genome Center, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.

Nature communications
|February 14, 2026
PubMed
概括

这项研究引入了GenT,这是一种基于基因的关联测试的新框架,用于识别阿尔茨海默氏症和精神分裂症等复杂疾病的新药标. 实验验证证证实了对阿尔茨海默病的潜在治疗方法.

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