儿童近视控制干预措施的临床有效性和成本效益:单中心回顾性研究
Daohuan Kang1, Lu Yuan1, Carla Lanca2,3
1Department of Ophthalmology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou, 310052, Zhejiang Province, China.
Scientific reports
|February 14, 2026
概括
重复的低水平红光 (RLRL) 治疗在近视控制方面显示出最高的疗效,一些患者出现轴缩短. 近视控制眼镜镜片 (MCSL) 为儿童近视的管理提供了最好的成本效益.
科学领域:
- 眼科医生 眼科 眼科
- 儿科光学测量 儿科光学测量
- 临床光学 临床光学
背景情况:
- 近视是儿童日益严重的公共卫生问题.
- 有效的近视控制策略对于预防高近视和相关的眼部并发症至关重要.
- 在现实环境中比较各种干预措施对于临床决策至关重要.
研究的目的:
- 为了比较四种近视控制干预措施的一年临床疗效和成本效益:单眼镜 (SVL),近视控制眼镜镜 (MCSL),正眼镜 (Ortho-K) 和重复低水平红光 (RLRL) 治疗.
- 通过追溯观察队列研究,在现实环境中评估干预措施.
- 确定与SVL相比,每个积极干预的增量成本效益比率 (ICER).
主要方法:
- 对206名年龄在8-14岁的近视儿童进行了回顾性观察队列研究.
- 干预措施包括SVL (n=50),MCSL (n=60),Ortho-K (n=44) 和RLRL (n=52).这些干预措施包括SVL (n=50),MCSL (n=60),Ortho-K (n=44) 和RLRL (n=52).
- 主要结果:一年后轴长度 (AL) 和球体等效折射率 (SER) 的变化. 第二次结果:ICER.
主要成果:
- 与SVL相比,所有积极干预措施都显著减少了AL延长 (平均AL变化:0.42毫米/年).
- RLRL显示了最高的疗效 (平均AL变化:0.06毫米;相对于SVL的86.0%),31%的人经历了轴缩短.
- 最具成本效益的干预措施是MCSL (0.23毫米AL变化;45.2%的疗效),每0.1毫米AL节省151.69美元,其次是RLRL (184.13美元). 整形-K (0.18毫米的AL变化;57.5%的疗效) 具有最高的ICER (400.42美元).
结论:
- RLRL治疗在近视控制中表现出最高的一年疗效,在一小部分患者中观察到轴缩短,需要在RCT中进一步调查.
- MCSL眼镜镜片代表了最具成本效益的近视控制选项,平衡有效性和经济可行性.
- 整形-K是非常有效的,但与MCSL和RLRL相比,与更高的财务成本有关.
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