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Updated: Feb 16, 2026

Deciphering the Structural Effects of Activating EGFR Somatic Mutations with Molecular Dynamics Simulation
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索尔提林通过限制EGFR转导功能来表现出类似瘤抑制剂的活性

E Lapeyronnie1, C Granet1, J Tricard1,2

  • 1UMR Inserm 1308 CAPTuR, Contrôle de l'Activation cellulaire, Progression Tumorale et Résistance thérapeutique and Chaire de Pneumologie Expérimentale, Université de Limoges, Faculté de Médecined, Limoges, CEDEX, France.

Oncogene
|February 14, 2026
PubMed
概括

索尔提林是一种调节细胞质表皮生长因子受体 (EGFR) 的蛋白质,可能在肺癌中起到瘤抑制作用. 它的表达可以预测抗EGFR疗法的效果.

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