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Lateral Root Inducible System in Arabidopsis and Maize
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更高阶的重复结构反映了玉米中间体和旋的不同进化路径.

Rebecca D Piri1, Mingyu Wang1, M Cinta Romay2

  • 1Institute of Bioinformatics, University of Georgia, Athens, GA, 30602, USA.

Genome biology
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概括
此摘要是机器生成的。

高级重复 (HOR) 在玉米卫星DNA中很常见. 虽然与中间体功能无关,但旋中保存的HOR模式可能会驱动介质驱动,影响基因组进化.

关键词:
阿拉比多普西斯 (Arabidopsis) 是一种植物.中心的中心 (Centromere)霍尔 (HOR) 是一个小时.按 按 是一个按.玉米 玉米 玉米 是 一种梅奥特驱动器的驱动器卫星DNA是卫星中的DNA.

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科学领域:

  • 基因组学就是基因组学.
  • 分子生物学分子生物学
  • 植物科学 植物科学

背景情况:

  • 卫星DNA的特点是重复的串联阵列,集中在像中心体这样的低重组基因组区域.
  • 这些卫星阵列可以具有称为高阶重复 (HOR) 的复杂结构,可能会影响它们的功能.
  • 玉米表现出独特的卫星DNA分布,无论是在中间体 (与kinetochore蛋白相互作用) 和旋 (参与介质驱动) 中.

研究的目的:

  • 调查玉米中间体和旋中高阶重复 (HOR) 的存在和特征.
  • 为了确定特定的HOR模式是否与玉米中间体和旋的功能有关.
  • 了解HORs在玉米基因组进化和介质驱动中的潜在作用.

主要方法:

  • 产生的13个重复敏感基因组组合玉米和teosinte.
  • 开发和应用基于图形的新型管道 (HiReNET) 用于HOR分类.
  • 使用基因组组件和功能标记器,分析中心和旋区域的HOR分布.

主要成果:

  • HORs在玉米卫星DNA中广泛存在,但通常以低频,小的模式出现,与人类中位粒体中的大块不同.
  • 大约38%的中心体CentC单体是HOR的一部分,没有单一的HOR类主导功能中心体.
  • 玉米旋显示了更有组织的HOR分布,大旋包含了兆基尺度的相似性块和重复的HOR模式,可能会驱动介质驱动.

结论:

  • 在所有主要的玉米卫星阵列中存在高阶重复 (HOR).
  • 没有特定的HOR与中间体功能相关;然而,在旋相似性块内保留的HOR模式可能会促进介质驱动.