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Updated: Feb 17, 2026

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转录因子E4BP4的缺乏抑制了血管损伤后的新极限形成

Fumie Ohtomo1, Kikuo Isoda2, Tomiharu Niida3

  • 1Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan.

Atherosclerosis
|February 15, 2026
PubMed
概括

在血管损伤后,E4BP4缺乏在小鼠中显著降低了neointimal形成和炎症性细胞因子. 这表明E4BP4抑制可能是血管炎症的治疗策略,包括塔卡亚苏动脉炎 (TAK).

关键词:
细胞因子 (cytokines) 是一种细胞因子.E4 结合蛋白 4 4 的结合蛋白炎症 炎症是一种炎症.这是新亲密的.

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