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向准确的穿皮CO2传感:使用与时间相关的单光子计数的行为模型

Hakan Burak Karli¹, Isil Isiksalan², Tuna B Tufan²

¹Institute for Quantitative Health Science and Engineering, Michigan State University, 775 Woodlot Dr, East Lansing, MI, 48824, USA; Department of Electrical and Computer Engineering, Michigan State University, 428 S Shaw Ln, East Lansing, MI, 48824, USA.

Biosensors & bioelectronics

|February 15, 2026

概括

一个新的模型估计了通过皮肤检测二氧化碳的光寿命. 该工具有助于开发用于临床和门诊使用的先进通风监测设备.

科学领域:

生物医学工程生物医学工程
光学传感技术的技术

背景情况:

透皮CO2传感对于评估通风的有效性至关重要.
现有的方法在准确性和实时监控方面可能存在局限性.

研究的目的:

开发一种行为模型来估计快速光信号寿命.
提高基于生命周期的皮肤穿二氧化碳传感系统的准确性和适用性.

主要方法:

实现了一个模拟完整光学和电子信号链的模型.
利用与时间相关的单光子计数 (TCSPC) 和光倍增器 (SiPM).
嵌入的非理想性,如暗计数,后脉冲,交叉声和激发泄漏.

主要成果:

在环境二氧化碳水平下恢复光寿命时达到86% - 93%的准确性.
成功地解决了光寿命短至3.5 ns.
由于噪音和降低衰变斜率,在较短的寿命中发现了性能下降.

结论:

开发的模型准确地估计了二氧化碳传感的光寿命.
该模型显示了指导改进二氧化碳监测设备的开发的潜力.
这些发现支持了临床和门诊CO2监测应用的进步.

关键词:

生物医学光学传感器临床呼吸评估临床呼吸评估光灯的寿命估计非侵入性的二氧化碳监测监测.光学气体检测仪的光学气体检测仪生理监测是指对身体进行生理监测.

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