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Updated: Feb 17, 2026

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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抑制HB-EGF的多种策略:与受体结合的干扰,生殖区脱落和母细胞信号的干扰

Andrii Siromolot1, Dariia Zhukova2, Svitlana Romaniuk2

  • 1Department of Molecular Immunology, Palladin Institute of Biochemistry of the NAS of Ukraine, 9 Leontovycha Street, Kyiv, 01054, Ukraine; Department of Technologies of Medical Diagnostics and Treatment, ESC "Institute of Biology and Medicine" of Taras Shevchenko National University of Kyiv, 2 Hlushkova Avenue, Kyiv, 03022, Ukraine.

Biochimie
|February 15, 2026
PubMed
概括

无毒的甲状腺毒素类似物CRM197和SbB阻断结合氨酸的EGF类生长因子 (HB-EGF) 从结合瘤细胞受体. 结合HB-EGF向策略可能会减少癌细胞的增殖,并诱导细胞死亡.

关键词:
甲状腺毒素的B亚单元.在HB-EGF的基础上.肝素是一种肝素.繁殖活动是一种繁殖活动.蛋白酶抑制剂是一种蛋白酶抑制剂.关于SRM197 的文章.

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