预防青少年接种疫苗后昏迷和昏迷:基于临床干预的随机对照试验
Michael J Smith1, Theresa A Harrington2, Richard J Chung3
1Department of Pediatrics; Duke Human Vaccine Institute, Duke University, Durham, NC.
The Journal of pediatrics
|February 15, 2026
概括
使用Buzzy®和视频游戏的联合干预显著减少了接种疫苗的青少年的昏前期. 这种方法还降低了疫苗接种后的疼痛,提供了一种有效的分心方法.
科学领域:
- 儿科医疗保健服务 儿科医疗保健服务
- 疼痛管理 疼痛管理
- 青少年医学 青少年医学
背景情况:
- 在青少年接种疫苗后,昏迷和昏迷是常见的不良事件.
- 之前的研究已经使用了前眼作为眼的替代品,因为它的发病率更高.
- 需要有效的干预措施来缓解这些血管反应.
研究的目的:
- 为了评估一个涉及Buzzy® (振动/冷却包) 和视频游戏分心的联合干预措施的有效性.
- 评估这项干预措施对减少疫苗接种后失眠前和失眠发病率的影响.
- 探索二次结果,包括焦虑,疼痛减轻和干预的可接受性.
主要方法:
- 一项随机对照试验对10至14岁的青少年进行,这些青少年接受了肌内注射疫苗.
- 参与者被分配到联合干预组 (Buzzy® + 视频游戏) 或标准护理控制组.
- 测量的主要结局是降低了临床失眠发生率.
主要成果:
- 综合干预组显示,与对照组相比 (48%,P = 0.02) 临近昏的发生率显著降低 (36%).
- 在干预组中,疫苗接种后的疼痛评分也降低了 (平均Wong-Baker Faces疼痛评分为2.5对3.3,P = 0.006).
- 该干预被发现是可接受的参与者.
结论:
- 结合Buzzy®和视频游戏的临床干预措施在疫苗接种期间有效降低青少年的失眠前期.
- 抑郁症的减少似乎是由疫苗接种后疼痛的减少所介导的.
- 这种干预提供了一种实用和可接受的方法来改善青少年的疫苗接种经验.
更多相关视频
14:09Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
22.0K
05:48Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
Published on: September 21, 2018
10.6K
相关概念视频
01:26Coronary Artery Disease IV: Preventive Measures
737
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
737
01:28Dosage Regimens: Designs and Approaches
347
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
347
01:26Pharmaceutical Poisoning: Treatment Strategies
17
Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...
17
01:28Acute Coronary Syndrome IV: Interprofessional Care
309
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
309