突接口:在从细胞到人类的交叉点
1Division of Rheumatology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute of Arthritis and Rehabilitation, Vienna, Austria.
概括
在炎症性关节炎中检测膜炎症是具有挑战性的. 未来的进步需要混合方法来评估协同体作为一个多维接口.
科学领域:
- 风湿病学和免疫学
- 生物医学工程 生物医学工程
- 临床医学 临床医学
背景情况:
- 突结合了关节内的免疫学,机械,感官和解剖学信号.
- 在类风湿性疾病中,交膜炎症是一种复杂的生物学和临床过程.
- 目前用于检测和监测突炎的方法在可靠性和临床结果相关性方面存在局限性.
研究的目的:
- 为了将协同膜构成一个多维接口.
- 探索临床检测和监测突炎的挑战.
- 提出评估炎症性关节炎疾病活动的未来方向.
主要方法:
- 审查来自细胞模型,临床检查和成像研究的证据.
- 免疫 - 突突相互作用的分析.
- 整合新兴的监测策略.
主要成果:
- 临床联合评估显示中等可靠性和有限的同意与患者报告.
- 像超声波和MRI这样的成像模式可以改善膜炎的可视化,但并没有持续改善临床结果.
- 在改善检测和有效的治疗决策之间仍然存在差距.
结论:
- 交叉膜作为一个多维接口,连接生物学,解剖学,感知和技术.
- 炎症性关节炎的未来进展取决于混合评估方法.
- 为了监测疾病活动,超越单一模式,向基于接口的评估迈进至关重要.
相关概念视频
Structural Joints: Synovial Joints
7.4K
Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
7.4K
Joints
35.9K
Joints, also called articulations or articular surfaces, are points at which ligaments or other tissues connect adjacent bones. Joints permit movement and stability, and can be classified based on their structure or function.
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
35.9K
Development of the Limb Synovial Joints
2.4K
Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
2.4K
Introduction to Joints
5.0K
The adult human body usually has 206 bones, and except for the hyoid bone in the neck, each bone is connected to at least one other bone. Joints are the location where bones come together. Many joints allow for movement between the bones. At these joints, the articulating surfaces of the adjacent bones can move smoothly against each other. However, the bones of other joints may be joined by connective tissue or cartilage. These joints are designed for stability and provide little or no...
5.0K
Structural Classification of Joints
7.5K
Joints, also known as articulations, are classified based on their structural characteristics, i.e., based on whether the articulating surfaces of the adjacent bones are directly connected by fibrous connective tissue or cartilage, or whether the articulating surfaces contact each other within a fluid-filled joint cavity. These differences serve to divide the joints of the body into three structural classifications.
A fibrous joint is where the adjacent bones are united by fibrous connective...
A fibrous joint is where the adjacent bones are united by fibrous connective...
7.5K
Knee Joint
3.4K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
3.4K


