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Updated: Feb 17, 2026

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
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Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

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通过调节 BAX/BCL2 亡信号传递和维护细胞,内皮细胞和管状细胞完整性,L-卡尼丁减轻了甲基酸诱导的毒性

Özlem Türkoglu1, Zafer Usta2, Kemal Çavdarlı3

  • 1Department of Radiology, Hamidiye Faculty of Medicine, University of Health Sciences, İstanbul, Turkey.

Journal of applied toxicology : JAT
|February 15, 2026
PubMed
概括

通过降低氧化应激和保持细胞完整性,L-卡尼丁 (LCR) 能够防止甲基酸 (MTX) 诱导的损伤. 这项研究表明,LCR通过重新平衡亡并维持脏结构来减轻MTX脏毒性.

关键词:
在BAX/BCL2中.对于L-卡尼丁来说,它是一种内皮质功能障碍 在内皮质功能障碍甲基特雷克萨酸盐的使用方法线粒体的亡是线粒体的亡.神经保护神经保护毒性 毒性 毒性氧化应激是一种氧化应激.

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