阶段特定的双位点β跨交替电流刺激不同影响与运动抑制性能相关的功能连接性
Tingting Zhu1,2, Alexander T Sack1,2, Inge Leunissen1,2
1Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Human brain mapping
|February 16, 2026
概括
双部位的横交替电流刺激 (tACS) 调节了大脑区域之间的β频段同步. 虽然小组表现没有改变,但tACS改变了大脑活动如何预测抑制控制和运动反应.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 大脑刺激 大脑刺激
背景情况:
- 抑制性控制涉及前基底腺网络中协调的β频段活动.
- 贝塔同步在运动抑制中的确切因果作用需要进一步研究.
研究的目的:
- 调查β同步在运动抑制中的因果作用.
- 探索双部位跨交替电流刺激 (tACS) 对功能连接和抑制控制的影响.
主要方法:
- 在52名健康参与者中,双站点tACS应用于右下额头 (rIFG) 和左主运动皮质 (lM1).
- 参与者在相位,反相位和假刺激条件下执行了停止信号任务.
- 评估了功能连接和行为表现.
主要成果:
- 在相位tACS增加了rIFG-lM1连接;反相位tACS降低了它.
- 没有观察到在停止信号任务执行方面在组级发生显著的变化.
- 探索性分析显示,tACS改变了β同步和抑制/运动性能之间的关系.
结论:
- 双站点β-tACS可以双向调节rIFG-M1连接以相位依赖的方式.
- 尽管平均性能没有变化,但tACS选择性地改变了beta同步如何预测停止和电机执行.
- 这些发现为使用tACS来研究或规范临床人群中的抑制性网络动态提供了机械洞察力.
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