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抗生素辅助剂的临床前药理动力学和药理动力学

Viet Tin Pham1, David M P De Oliveira2, Andy Kuo1

  • 1Centre for Integrated Preclinical Drug Development, School of Biomedical Sciences, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, St Lucia Campus, Brisbane, QLD 4072, Australia.

ACS infectious diseases
|February 16, 2026
PubMed
概括

抗菌素耐药性 (AMR) 需要新的策略. 与现有药物相结合的抗生素辅助剂显示出希望,但它们的药理动力学/药理动力学 (PK/PD) 关系需要超出传统MIC方法的新型分析方法.

关键词:
抗生素辅助剂 抗生素辅助剂抗微生物耐药性 抗微生物耐药性瞬间最小抑制度 (MICi)小鼠感染模型的小鼠感染模型.药理动力学/药理动力学 (PK/PD) 分析值度 (CT) 是指值度 (CT) 的值.

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