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Updated: Feb 17, 2026

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从2010年到2025年,中国猪流感病毒的流行程度和异质性:系统性审查和元分析

Xiutao Yang¹, Qingxia Gao², Zhaofang Xi²

¹National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, hzau.edu.cn.

Transboundary and emerging diseases

|February 16, 2026

概括

猪流感病毒 (SIV) 在中国普遍存在,总的综合流行率为30.3%. 影响SIV发病率的关键因素包括诊断方法,地理位置和病毒基因型,这凸显了针对性控制策略的必要性.

科学领域:

兽医流行病学兽医流行病学
公共卫生监督是对公共卫生的监督.
病毒学病毒学

背景情况:

猪流感病毒 (SIV) 在中国流行,对猪业和公共卫生构成重大威胁.
准确的流行病学数据对于有效的风险评估和干预开发至关重要.

研究的目的:

估计从2010年到2025年,中国的SIV全国综合流行率.
确定不同地区和方法的SIV流行异质性的关键来源.

主要方法:

按照PRISMA指导方针进行系统的元分析.
搜索了六个数据库寻找符合条件的研究,其中包括73项研究,包含411,930个样本.
采用随机效应模型进行聚合流行率估计和子组分析,以探索异质性.

主要成果:

综合的SIV患病率估计为30.3% (95% CI: 24.5%-36.4%),具有显著的异质性 (I2 = 100%).
患病率根据诊断方法 (血清学:37.1%与病毒学:2.6%),地理区域 (中国西南部:54.3%) 和病毒基因型 (H1>H3) 有显著差异.
发现了出版偏差,这表明了对聚合流行率的潜在高估.

结论:

艾滋病病毒在中国很普遍,但其流行率显示出相当大的时空和方法变化.
单一的国家患病率数据不足以进行全面的风险评估;有针对性的,具体的情境监测和控制策略至关重要.
这项研究为基于证据的干预提供了关键的流行病学基线,承认由于出版偏差而导致的潜在高估.

关键词:

中国中国中国中国.流行病学监测流行病学监测流行病学监测不同质性的异质性这是一个元分析.患病率的流行情况.猪流感病毒猪流感病毒

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