修改的水下内镜粘膜切除大肠的可行性研究
Kaizo Kagemoto1, Koichi Okamoto1, Yoji Takeuchi1,2
1Department of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
DEN open
|February 16, 2026
概括
修改的水下内镜粘膜切除 (M-UEMR) 为结直肠多提供了安全有效的替代方案. 这种技术改善了可视化,在困难的情况下实现了高R0切除率.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 结肠直肠癌查 结肠直肠癌查
背景情况:
- 水下内镜粘膜切除 (UEMR) 是结直肠瘤的标准,但面临着可视化挑战.
- 困难包括脏的液体,不足的水和出血,阻碍清晰的内镜视图.
研究的目的:
- 为了研究修改后的UEMR (M-UEMR) 技术的安全性和有效性.
- M-UEMR涉及水下捕捉,然后进行气体下切除.
主要方法:
- 一个单中心前性临床试验招募了患有10-25毫米结直肠息肉的患者.
- M-UEMR程序涉及水下捕鱼,水分提取和二氧化碳吸入用于切除.
- 测量结果包括R0切除率,不良事件,块切除率和粘膜下组织厚度.
主要成果:
- 该研究招募了40名患者,达到80%的R0切除率.
- 没有观察到与程序相关的不良事件.
- 整体切除率为92.5%. 在整体切除中,切除率为92.5%.
结论:
- 修改后的UEMR (M-UEMR) 显示出高的R0切除率和安全的特征.
- M-UEMR是结直肠多瘤的有希望的替代方案,特别是当清晰的可视化具有挑战性时.
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