基于光纤的高速,广场的PS-OCT系统,具有实时表面Stokes反,用于循环输入极化
Yaping Shi1, Jingjiang Xu1, Zhaoyu Gong1
1Department of Bioengineering, University of Washington, Seattle, Washington 98105, USA.
Biomedical optics express
|February 16, 2026
概括
我们开发了一种高速偏振灵敏光学连贯性断层扫描 (PS-OCT) 系统,用于体内双断层成像. 一种新的反机制稳定了两极分化,使得诊断的详细口腔成像成为可能.
科学领域:
- 生物医学光学 生物医学光学
- 医疗成像医学成像
- 光学连贯性断层扫描技术
背景情况:
- 基于光纤的偏振灵敏光学连贯性断层扫描 (PS-OCT) 系统面临着输入偏振状态 (SOP) 不稳定的挑战,特别是在手持设备中.
- 精确的双折射图像对组织的成像需要稳定和可控的光极化.
- 现有的方法可能缺乏全面体内诊断所需的速度和视野.
研究的目的:
- 为提供高速,广场,基于纤维的PS-OCT系统,用于可靠的体内双断率成像.
- 引入实时反机制,以稳定基于光纤的PS-OCT的输入SOP.
- 为了证明该系统能够对组织床进行详细的结构和极化分辨率成像的能力.
主要方法:
- 开发一种基于光纤的PS-OCT系统,使用600kHz扫源激光器.
- 实时样本表面Stokes向量反机制的实现,以稳定事件循环极化.
- 系统优化以平衡轴分辨率 (~37.8微米) 和减轻极化模式分散 (PMD) 在20纳米带宽下,实现>200灭绝比.
- 幻影研究用于可重复性验证和在人体前腔口腔的体内成像,视野为42×42mm2.
主要成果:
- 实时SOP反机制显示出高可重复性 (中位角标准偏差为6.52°).
- 该系统实现了广的视野 (42×42mm2),具有详细的结构和极化对比度.
- 能够同时评估面膜面向,牙双断,以及早期组织异常.
结论:
- 开发的高速,广场PS-OCT系统为体内双断片成像提供了简化和强大的解决方案.
- 实时SOP稳定技术克服了固有的基于纤维的不稳定性.
- 这项技术有助于在牙科和软组织成像中进行先进诊断的临床翻译.
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