可穿戴式频域近红外光谱 (FD-NIRS) 系统
Shashikant Lahade1, Siavash Yazdi2, Nicholas Ross1
1Department of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.
Biomedical optics express
|February 16, 2026
概括
一个新的可穿戴频域近红外光谱 (FD-NIRS) 系统使实验室外的实时组织氧化监测成为可能. 这款紧型设备推进了用于持续健康评估的非侵入性光学光谱学.
科学领域:
- 生物医学光学 生物医学光学
- 可穿戴技术可穿戴技术
- 频谱学是一种光谱学.
背景情况:
- 频域近红外光谱 (FD-NIRS) 是一种非侵入性技术,用于量化组织组成和新陈代谢.
- 目前的FD-NIRS仪器通常是大型和复杂的,限制其用于研究环境.
- 需要便携式FD-NIRS系统,用于在自然环境中持续监测.
研究的目的:
- 开发一种新的,实时的,多频穿戴式FD-NIRS系统.
- 将FD-NIRS技术缩小为健康监测中的更广泛应用.
- 为了证明用于可穿戴应用的定量FD-NIRS的可行性.
主要方法:
- 开发了一个可穿戴的FD-NIRS系统,使用定制的特定应用集成电路 (ASIC).
- 集成685nm和850nm激光二极管和光倍增器 (SiPM) 探测器.
- 使用组织模拟幻象评估了系统的准确性,并通过前臂遮测量证明了概念验证.
主要成果:
- 在14.7Hz的测量速率下,实现了高精度的光学性能 (吸收:0.0007mm-1,减少散射:0.08mm-1).
- 这个可穿戴设备是紧的 (7x3x3厘米) 和轻量级的 (37g没有电池).
- 在单个频率上展示了高达1kHz的实时测量能力.
结论:
- 开发的可穿戴FD-NIRS系统可用于定量组织光学光谱学.
- 这项技术可以将FD-NIRS应用扩展到持续监控和自然环境中.
- 该系统代表着可穿戴健康监测的重大进步.
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