肝细胞生长因子作为突炎炎和类风湿性关节炎治疗耐药性的驱动因素

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Updated: Feb 17, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

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Quang Minh Dang1,2,3, Ryu Watanabe1, Takeshi Iwasaki4

  • 1Department of Clinical Immunology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.

Frontiers in immunology
|February 16, 2026
PubMed
概括

肝细胞生长因子 (HGF) 通过激活突纤维细胞并创建反循环,驱动类风湿性关节炎 (RA) 中的炎症. 用萨沃利提尼布向HGF-c-Met通路显示出治疗RA和克服治疗耐药性的前景.

关键词:
肝细胞生长因子 肝细胞生长因子干白素-6 (IL-6) 之间的关系类风湿性关节炎 类风湿性关节炎状纤维母细胞 状纤维母细胞这是一种类似收费的受体.

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