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Updated: Feb 17, 2026

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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低剂量环胺与标准免疫抑制疗法相结合,改善了严重无形成性贫血的早期反应率

Hong Pan1,2,3, Zhen Gao1,2,3, Lele Zhang1,2,3

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.

Frontiers in immunology
|February 16, 2026
PubMed
概括

将低剂量环胺 (CTX) 添加到标准免疫抑制疗法 (IST) 中,改善了严重无形成性贫血 (SAA) 患者的早期反应率. 这种组合疗法显示出可控毒性,为SAA/VSAA提供了有前途的新治疗选择.

关键词:
抗胆小细胞球蛋白是一种抗胆小细胞球蛋白.环酸胺的使用方法免疫抑制疗法是一种免疫抑制疗法.严重的无塑性贫血.血栓形成素受体激活剂 血栓形成素受体激活剂

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