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Updated: Feb 17, 2026

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巨细胞的AMPKα1缺乏会通过TNF-α-FBP2信号破坏肌再生和肌干细胞功能

Lisha Zhu1,2,3,4, Yu Wang2,3, Xinmeng Shi2,3

  • 1Central Laboratory, Peking University School and Hospital of Stomatology, Beijing 100081, China.

International journal of biological sciences
|February 16, 2026
PubMed
概括

巨细胞AMP激活蛋白激酶 (AMPK) α1对于肌愈合至关重要. 其缺乏会通过TNF-α-FBP2通路损害干细胞功能和肌修复,突出FBP2的作用.

关键词:
腺单酸盐激活的蛋白质激酶.果糖-1,6-双酸盐酶2的使用巨细胞是一个巨细胞.肌再生 肌再生肌干细胞/原始细胞

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