如何平衡可持续性和标本保护
1The Johns Hopkins BioBank, Genetic Resources Core Facility, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21287, USA.
F1000Research
|February 16, 2026
概括
实施集中式生物银行服务大大降低了能源消耗和环境影响. 这种方法通过高效的存储和治理确保了样本完整性和研究连续性,证明了生物医学研究基础设施的可持续模式.
科学领域:
- 生物医学研究基础设施
- 生物银行和标本管理
- 可持续实验室实践 可持续实验室实践
背景情况:
- 生物库对于研究至关重要,但由于超低温 (ULT) 存储和冗余系统,它们耗费大量能源.
- 在不损害样本质量或研究连续性的情况下减少环境影响是一个关键的挑战.
- 服务中心提供了一个可扩展的解决方案,其治理能力超过了个别实验室.
研究的目的:
- 评估在学术生物银行服务中心内整合可持续性,质量和应急规划的可行性.
- 展示集中存储和机构治理如何减少环境影响并确保标本的保护.
- 在大型学术环境中评估特定ULT存储策略和治理政策的有效性.
主要方法:
- 在约翰霍普金斯大学的34个部门进行了全面的冷藏柜审计,评估了年龄,利用率和效率.
- 实施了鼓励生物标本迁移到集中存储的政策,优先考虑蒸汽相液 (LN2) 和节能MVE Variō系统.
- 机构治理要求在购买新的冷器之前对集中化选项进行评估,并得到外展倡议的支持.
主要成果:
- 确定了近1300个ULT冷器,其中70%以上超过了它们的中位寿命.
- 将其整合为由生物银行管理的冷场,减少了机构的能源需求,并改善了监控.
- 集中存储,利用LN2和Variō单元,提供稳定,节能的存储,制不受控制的冷扩张.
结论:
- 学术服务中心可以有效地整合可持续性,质量和应急规划.
- 约翰霍普金斯生物银行案例研究表明,共享资源和机构治理为减少环境影响提供了切实可行的框架.
- 这种模式确保了不妥协的标本保护,同时解决了生物银行的能源和成本强度.
相关概念视频
01:02Sample Handling
2.7K
Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
2.7K
01:19Key Techniques in Microbiology
2.6K
Aseptic techniques prevent contamination, ensure experimental accuracy, and protect researchers and microbial cultures. These techniques are essential in clinical, industrial, and research settings where sterility is required.Maintaining Sterility in Laboratory PracticesScientists maintain sterility by sterilizing tools with heat or chemicals, disinfecting work surfaces, and handling cultures in controlled environments. Working near an open flame or within a laminar flow hood reduces the risk...
2.6K
01:20Preparation of Samples for Electron Microscopy
7.3K
To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
7.3K