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患有白血病的儿科患者的皮肤:一个诊断和治疗的挑战

María T Berumen Murra¹, Verónica Martínez García¹, Guadalupe Maldonado Colín¹

¹Department of Dermatology, National Medical Center 20 de Noviembre Institute of Security and Social Services for State Workers (ISSSTE), Mexico City, MEX.

|February 16, 2026

概括

菌病是一种罕见的真菌感染,在免疫力低下的儿童,特别是患有白血病的儿童中,可能是致命的. 早期识别皮肤病变对于及时干预和改善儿科发病例的结果至关重要.

科学领域:

菌类学菌类学是指菌类学.
传染性疾病传染性疾病
儿科瘤学儿科瘤学

背景情况:

菌病是一种罕见的机会性真菌感染.
它主要影响免疫功能受损的患者,往往导致诊断延迟和不良结果.
非特定的临床表现有助于诊断挑战.

研究的目的:

在患有复发性急性B细胞淋巴细胞白血病的儿科患者中报告侵袭性瘤病例.
强调识别免疫受损儿童皮肤表现的重要性.
强调在管理侵入性真菌感染时需要多学科管理.

主要方法:

一个八岁的男性患有复发性急性B细胞淋巴细胞白血病和中枢神经系统干扰的病例报告.
临床表现包括发烧,中性质衰竭和扩散皮肤病变.
通过组织病理学检查和真菌培养物证实了诊断.

主要成果:

患者患有扩散性皮肤病变,从斑点发展为死斑斑块.
尽管使用了广泛的抗生素和抗真菌疗法 (安福特素B,伏利可纳),但患者的病情迅速恶化.
结果是致命的,有败血症休克和确定的侵入性化症.

结论:

在免疫功能低下的儿科患者中,早期识别皮肤菌症至关重要.
迅速和多学科的管理对于改善临床结果至关重要.
这一案例凸显了儿科白血病患者中菌病的攻击性.

关键词:

皮肤疾病皮肤疾病化器 (Fusarium) 是一种化器.免疫功能受损的宿主.这些是mycoses.机会性感染机会性感染

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