在食物冲击期间,低于值的氨酸友好症可能掩盖了氨酸友好性食道炎:一个儿科病例系列
Mark Mahon1,2, Amanda Muir1,2
1Division of Gastroenterology, Hepatology, and Nutrition Children's Hospital of Philadelphia Philadelphia Pennsylvania USA.
JPGN reports
|February 16, 2026
概括
儿童的食道食物影响可以表明eosinophilic食道炎 (EOE). 即使最初的低乙酸细胞计数,随访和重复内镜对于准确的EoE诊断至关重要.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 过敏和免疫学 过敏和免疫学
- 胃肠道病理 胃肠道病理
背景情况:
- 食道食物冲击 (EFI) 是儿科急诊室的一个常见表现.
- 在EFI期间的初始内镜活检可能会显示亚诊断性乙素细胞计数,使诊断复杂化.
- 性食道炎 (EoE) 是食道的过敏性炎症性疾病.
研究的目的:
- 评估EFI儿科患者纵向随访的需要.
- 为了确定具有亚诊断性乙酸细胞计数的EFI是否可以进展到确定的EoE诊断.
- 突出充分的活检采购和重复内镜对于EoE诊断的重要性.
主要方法:
- 对经过内镜评估的患有EFI的儿科患者进行了回顾性图表审查.
- 分析食道活检中的乙氨基酸计数 (乙氨基酸每高功率场 - - HPF).
- 患者的长度评估最初的亚诊断性乙氨基酸细胞数量 (1-14/HPF).
主要成果:
- 确定了四名儿科患者,EFI和亚诊断性乙氨基酸细胞计数 (1-14/HPF).
- 在重复内镜检查 (≥15/HPF) 后,所有四名患者都显示了食管内细胞的增加.
- 在所有被评估的患者中确诊了性食道炎 (EoE).
结论:
- 食道食物冲击 (EFI) 可能是eosinophilic食道炎 (EoE) 的初始临床表现.
- 在EFI期间的初始活检可能不符合EoE的诊断标准.
- 纵向跟踪,适当的活检采样和重复内镜对于儿科EFI病例中准确的EoE诊断至关重要.
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