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Updated: Feb 17, 2026

Analyzing the α-Actinin Network in Human iPSC-Derived Cardiomyocytes Using Single Molecule Localization Microscopy
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Published on: November 3, 2020

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细胞形状和成熟影响iPSC衍生的心肌细胞中的α-actinin-2张力

Palash K Dutta, Joshua M Toth1, Subramanian Sundaram2

  • 1Center for Engineering Mechanobiology and Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

APL bioengineering
|February 16, 2026
PubMed
概括

心肌细胞 (CM) 收缩涉及通过瘤细胞传递力. 这项研究使用了一种新型传感器,表明细胞形状和成熟会影响对体蛋白α-actinin-2的张力,影响心脏功能.

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