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基于传统中医的舌头特征的视觉评估与当前的癌症相比没有癌症史:一个匹配的病例对照研究

Maria Benxia Wu¹, Stella Stylianou², Yong-Kang Wu³

¹School of Health and Biomedical Sciences, STEM College, RMIT University, Bundoora, VIC, Australia.

Frontiers in medicine

|February 16, 2026

概括

某些舌头特征,如蜘蛛舌下静脉和牙痕迹,可能表明癌症存在. 然而,由于这项探索性研究的准确性和可靠性有限,这些发现需要进一步验证.

科学领域:

综合性瘤学综合性瘤学
传统中国医学 (TCM) 是一种
生物标志物发现发现

背景情况:

增加癌症存活率需要支持性护理,包括TCM.
舌头检查是TCM的一种常规诊断方法.
这项研究探讨了癌症幸存者与非癌症患者之间舌头特征的差异.

研究的目的:

调查癌症幸存者和没有癌症史的个人之间,视觉评估的舌头特征是否有所不同.
为了确定与癌症存在相关的特定舌头特征.
评估舌头特征在癌症检测中的潜在诊断效用.

主要方法:

一项与60名癌症幸存者和60名对照者的匹配病例对照研究.
标准化的舌头照片被盲目的中医医疗从业者分析.
使用后勤回归模型和统计测试 (FDR,Fleiss' κ,AUC) 来评估关联,可靠性和歧视.

主要成果:

六个舌头特征与癌症存在有关 (FDR q <0.05),包括剥离的涂层,蜘蛛舌下静脉,厚厚的涂层,紫色的身体和牙痕迹.
蜘蛛舌下静脉和牙痕迹特别与癌症有关.
评价者之间的可靠性轻微至中度 (κ ≈ 0.01-0.48),诊断歧视是适度的 (AUC 0.676-0.736).

结论:

在探索性分析中,特定的舌头特征与癌症有关.
目前的发现表明诊断效用有限,需要谨慎的解释.
用标准化定义进行进一步的研究,评价者培训和更大的前性研究对于临床翻译至关重要.

关键词:

癌症的生存率癌症的生存率个案控制研究研究.语言下静脉语言下静脉舌头图像图像语言图像舌头检查舌头检查传统的中国医药传统的中国医药.

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