Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Brain Imaging01:14

Brain Imaging

763
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
763

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Multivariate Patterns of Food Image Evaluations Distinguish Obesity: A Key Role of Highly Processed Foods.

Appetite·2026
Same author

Region-specific dysregulation of proline metabolic enzymes underlying mitochondrial dysfunction in the postmortem brains of patients with schizophrenia.

Journal of psychiatric research·2026
Same author

Psychometric properties of hierarchical psychiatric symptoms on the general population.

PLOS mental health·2026
Same author

Autistic symptoms in early psychosis are associated with mean diffusivity-dominant alterations in white matter tracts implicated in schizophrenia and autism spectrum disorder.

Asian journal of psychiatry·2026
Same author

Association between initial 30-day cumulative clozapine dose and risk of agranulocytosis: A nationwide register-based cohort study.

Psychiatry and clinical neurosciences·2026
Same author

Synergistic and redundant information dynamics exhibit dissociable alterations across schizophrenia and neurodevelopmental conditions.

Brain informatics·2026

相关实验视频

Updated: Feb 17, 2026

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.4K

数字双胞胎大脑:从连接器生成多任务行为,用于个性化治疗.

Yuta Takahashi1,2, Takafumi Soda1, Hiroaki Tomita2

  • 1Department of Information Medicine, National Center of Neurology and Psychiatry, Tokyo, Japan.

BME frontiers
|February 16, 2026
PubMed
概括

这项研究介绍了一个数字双胞胎大脑框架,它将一个人的大脑连接组与行为联系起来,使得精确的预测和个性化干预能够为精神病治疗提供帮助.

科学领域:

  • 神经科学是一个神经科学.
  • 计算精神病学是一种计算精神病学.
  • 数字双胞胎是一个数字双胞胎.

背景情况:

  • 个性化精神病学需要数字双胞胎模型来预测来自个体神经生物学的各种功能.
  • 目前的模型在将大脑结构连接到复杂的多任务行为方面面临挑战,这限制了临床应用.

研究的目的:

  • 引入和验证一个数字双胞胎大脑框架.
  • 为了将个体大脑连接体转化为神经行为动态的预测.
  • 为了实现个性化的功能调制和干预.

主要方法:

  • 一个新的2组件架构:一个超级网络,使用个人的连接组来个性化主网络.
  • 一个循环神经网络模拟参与者特定的行为和血液氧气水平依赖 (BOLD) 时间序列.
  • 梯度反向传播识别了用于目标功能调制的连接组操纵.

主要成果:

  • 该模型在预测行为选择方面实现了>90%的准确性,以及对反应时间 (r > 0.85) 和BOLD模式 (r = 0.84) 的高准确性.
  • 在形干预成功调节了目标功能.
  • 该框架复制了基于基线连接人群的治疗效果的现实的个人间变异性.

更多相关视频

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
06:11

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity

Published on: September 26, 2025

1.0K
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.6K

相关实验视频

Last Updated: Feb 17, 2026

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.4K
High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
06:11

High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity

Published on: September 26, 2025

1.0K
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.6K

结论:

  • 数字双胞胎大脑系统有助于对复杂的神经行为功能进行高准确度的形预测.
  • 它使这些功能的个性化调节成为可能,促进了个性化的精神病治疗.
  • 这种方法将大脑连接体直接与行为联系起来,为干预设计创造了一个机械化的平台.