由于Candida lusitaniae引起的儿科候选血症:临床和微生物学评估
Nisa Nur Tapaç1, Ümmühan Çay1, Özlem Özgür Gündeşlioğlu1
1Department of Pediatric Infectious Diseases, Faculty of Medicine, Cukurova University, Adana, Turkey.
Current medical mycology
|February 16, 2026
概括
菌 (Candida lusitaniae) 是儿童侵入性真菌感染的罕见原因,通常与潜在的疾病和危险因素有关. 可纳是一种关键的治疗方法,但在困难的病例中可能需要联合治疗.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 儿科医学 儿科医学
背景情况:
- 菌是侵袭性白病的不常见原因,特别是在儿童群体中.
- 了解儿童中C. lusitaniae candidemia的临床谱,治疗和结果对于有效的管理至关重要.
研究的目的:
- 调查儿童患者中C. lusitaniae candidemia的临床和微生物特征.
- 分析与C. lusitaniae血流感染相关的治疗方案和患者预后.
主要方法:
- 从2013年12月到2021年12月,对患有C. lusitaniae血流感染的儿科患者 (<18岁) 的回顾性分析.
- 收集的数据包括人口统计,潜在疾病,风险因素,抗真菌敏感性,治疗和结果.
- 使用VITEK® 2 Compact系统进行的抗真菌敏感性测试.
主要成果:
- 在395次候选血病发作中,C. lusitaniae占2.7%,患者中位数年龄为16个月.
- 常见的危险因素包括使用抗生素 (100%),中央静脉导管 (91%) 和机械通风 (63.6%).
- 整体30天死亡率为9%,其中接受组合治疗的患者有1人死亡.
结论:
- 虫疹 (Candida lusitaniae) 是一种罕见的医院病原体,在儿童中具有显著的潜在疾病和危险因素.
- 可纳是主要治疗方法,但对于耐火病例可能需要联合治疗;由于潜在的耐药性,要小心使用L-AmB.
- 及时移除中央静脉导管与儿科C. lusitaniae candidemia.的改善结果有关.
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