评估心脏病在严重孕产妇发病率中的作用:基于人口的队列研究
Kelly F Darmawan1, Elizabeth B Sherwin1, Stephanie A Leonard1
1Division of Maternal Fetal Medicine and Obstetrics, the Department of Pediatrics, Division of Neonatal and Developmental Medicine, and the Department of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California.
O&G open
|February 16, 2026
概括
患有心脏病的人在分娩期间和分娩后面临严重孕产妇死亡率 (SMM) 的风险显著增加. 这包括心脏和肺性SMM的几率特别高,强调需要有针对性的干预措施.
科学领域:
- 产科和妇科 产科和妇科
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 心脏病在怀孕期间是一个越来越令人担忧的问题.
- 了解心脏病和严重孕产妇死亡率 (SMM) 之间的关联对于改善孕产妇的结果至关重要.
研究的目的:
- 评估先前存在的心脏病与非输血严重孕产妇死亡率 (SMM) 风险之间的关联,在分娩期间住院和产后42天.
- 检查心脏病患者与没有心脏病患者之间的特定类型的SMM.
主要方法:
- 使用加利福尼亚州相关的出生证明和医院出院数据 (2007-2020) 的回顾性队列研究.
- 包括单独分娩 (怀孕20-44周).
- 使用诊断码识别患有心脏病的个体;主要结局是非输血SMM.
主要成果:
- 分析了超过580万例分娩;0.5%是患有心脏病的个体.
- 患有心脏病的个体的非输血SMM (AOR 6.88) 和输血SMM (AOR 4.69) 的几率明显更高.
- 观察到显著增加的心脏 (AOR 53.49) 和肺SMM (AOR 11.79) 的几率;非输血SMM事件在分娩住院期间更频繁.
结论:
- 以前存在的心脏病与所有类型的SMM风险显著增加密切相关,特别是心脏和肺部并发症.
- 这些发现强调了与怀孕期间心脏病相关的发病风险增加.
- 结果可以为有针对性的策略提供信息,以减轻分娩期间和分娩后的SMM.
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