尿病的流行病学和危险因素:来自SKIPOGH的见解,这是瑞士的一项基于人口的队列研究
Kevin Stritt1,2, Maude Plouvin1, Sandrine Estoppey Younes3
1Department of Urology, University Hospital Lausanne (CHUV), University of Lausanne, Lausanne, Switzerland.
Clinical kidney journal
|February 16, 2026
概括
瑞士的结石患病率低于北美,但高于亚洲. 糖尿病,家族病史和较高的肌素与现有的结石有关,而吸烟和低活动预测新的结石.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 结石是一个日益严重的全球健康问题,在全球范围内患病率各不相同.
- 欧洲关于结石患病率和发病率的数据仍然有限.
- 这项研究通过检查瑞士成年人口来解决数据稀缺的问题.
研究的目的:
- 为了确定瑞士结石的流行和发病率.
- 确定与结石相关的人口,生活方式和临床因素.
- 为未来预防结石的预防策略提供信息.
主要方法:
- 利用了瑞士项目对高血压基因 (SKIPOGH) 队列 (n=1128) 的数据.
- 在基线和3年后的随访中使用脏超声波和标准化问卷.
- 应用多变量逻辑回归来识别流行和发病结石的危险因素.
主要成果:
- 结石的患病率为5.6% (男性6.1%,女性5.1%);三年发生率为4.3%.
- 与糖尿病相关的流行的结石,家族病史和较高的血清肌素.
- 事件石头与积极吸烟,较低的体力活动和个人石头史有关.
结论:
- 瑞士结石的发病率位于北美和亚洲之间的比率.
- 糖尿病和家族病史是流行的结石的主要危险因素.
- 个人病史和体力活动不足预测了新的石头形成,指导了预防工作.
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