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中国甲状腺成像报告和数据系统对甲状腺恶性瘤风险分层进行了重新定义,显示了甲状腺显着低生态性,证明了诊断准确度的提高

Yingxue Bai¹, Mingxin Yu¹, Size Wu¹

¹Department of Ultrasound, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China.

|February 16, 2026

概括

一个经过修改的中国甲状腺成像报告和数据系统 (C-TIRADS) 具有重新定义的标记性低致病性标准,改善了甲状腺结节恶性瘤风险评估. 这种增强的C-TIRADS提供了更好的准确性,并使风险分层与预期的概率保持一致.

科学领域:

放射学和成像学放射学和成像学
在瘤学瘤学.
内分泌学在内分泌学.

背景情况:

通过超声波来区分良性和恶性甲状腺结节,这给诊断带来了挑战.
目前的甲状腺结节分类系统需要改进,以改善恶性瘤风险分层.

研究的目的:

评估修改后的中国甲状腺成像报告和数据系统 (C-TIRADS) 的诊断性能.
评估重新定义的显着低生殖性标准对分层甲状腺结节恶性瘤风险的影响.

主要方法:

对1,219名患有1,721个甲状腺结节的患者进行了回顾性分析,这些患者接受了超声波和随后的活检/治疗.
使用kappa统计数据评估了观察者之间的明显低生理性协议.
经过修改的C-TIRADS,经典的C-TIRADS和K-TIRADS的诊断性能 (灵敏度,特异性,准确性,AUC) 用基因病理学作为参考标准进行了比较.

主要成果:

重新定义显著的低生理性提高了观察者之间的一致性 (kappa从0.652到0.722) 并显著提高了灵敏度 (74.5%vs.15.1%) 和准确性 (86.8%vs70.8%).
与经典的C-TIRADS (88.2%,0.870) 和K-TIRADS (81.3%,0.857) 相比,修改后的C-TIRADS显示出更高的精度 (90.2%) 和AUC (0.908).
修改后的C-TIRADS类别的恶性病率为12.0% (4a),60.6% (4b),85.8% (4c) 和93.3% (5).

结论:

经过修改的C-TIRADS,其重新定义的标志性低致病性标准,显著改善了甲状腺结节恶性瘤风险分层的诊断性能.
这种增强的系统提供了与预期概率更紧密的风险评估,有助于临床决策.

关键词:

华人中文华人中文是什么意思恶性瘤是一种恶性瘤.分层分层是指分层分层.甲状腺是什么?甲状腺是什么?甲状腺成像报告和数据系统甲状腺结节甲状腺结节超声波超声波是指超声波的使用.

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