相关实验视频

Updated: Feb 17, 2026

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter
06:59

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter

Published on: March 31, 2022

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为更好的预测提供更好的数据:数据策划改善了对sgRNA/Cas9预测的深度学习

Tyler S Browne1, David R Edgell1, Gregory B Gloor1

  • 1Department of Biochemistry, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada.

PeerJ
|February 16, 2026
PubMed
概括

优化CRISPR-Cas9 (CRISPR相关蛋白9) 模型的数据输入可以提高抗菌应用的预测准确性. 这种以数据为中心的方法提高了跨细菌物种的Cas9预测模型的实用性.

关键词:
细菌CRISPR预测的方法这是一个CRISPR模型.在CRISPR的预测过程中.数据的清理数据的清理.高吞吐量测序的测序方法机器学习 机器学习模型建筑模型建筑SgRNA活动预测预测.

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