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塞费皮姆的混合肝细胞-胆固醇性肝损伤:一个病例报告

Reicelle Garcia¹, Kevan English²

¹Department of Internal Medicine, Creighton University Medical Center - Bergan Mercy, Omaha, NE 68124, United States.

World journal of clinical cases

|February 16, 2026

概括

塞费皮姆是一种常见的抗生素,很少会导致肝损伤. 及时停止塞费皮姆是治疗这种罕见的不良反应的关键,大多数患者康复.

科学领域:

药理学药理学是指药理学的学科.
内部医学内部医学
传染性疾病传染性疾病

背景情况:

塞菲皮姆是第四代类抗生素,具有针对阳性和阴性细菌的广泛活性.
它经常用于医院环境中的严重细菌感染,包括发烧性中性质疏松症和肺炎.
虽然通常是安全的,但已知的副作用包括局部反应,胃肠道问题和神经复杂症;肝损伤很少见.

研究的目的:

报告一个罕见的Cefepime诱导的肝损伤病例.
强调认识到和管理这种不利影响的重要性.

主要方法:

病例报告:一名73岁的男性住院时出现呼吸系统症状,并接受了万科米辛和塞菲皮姆治疗.
在治疗期间监测肝功能测试 (LFTs).
在LFT恶化时停止使用cefepime.

主要成果:

患者在开始服用cefepime后出现肝功能测试的恶化.
在停止服用塞费皮姆后,肝功能测试有所改善.
这位患者最终死于急性缺氧呼吸衰竭.

结论:

塞费皮姆可以导致罕见的肝损伤.
立即停止使用塞费皮姆是治疗塞费皮姆诱导的肝损伤的主要方法.
大多数Cefepime诱导的肝损伤病例没有并发症就会消失.

关键词:

案例报告案例报告时间的首席执行官.头类子素是什么?药物诱导的肝损伤是药物诱导的肝炎是一种肝炎.炎症炎症是一种炎症.通过氨基管炎.

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